Alginate and alginate composites for biomedical applications

نویسندگان

چکیده

Alginate is an edible heteropolysaccharide that abundantly available in the brown seaweed and capsule of bacteria such as Azotobacter sp. Pseudomonas Owing to alginate gel forming capability, it widely used food, textile paper industries; a lesser extent biomedical applications biomaterial promote wound healing tissue regeneration. This evident from rising use alginate-based dressing for heavily exuding their mass availability market nowadays. However, also has limitation. When contact with physiological environment, could gelate into softer structure, consequently limits its potential soft regeneration becomes inappropriate usage related load bearing body parts. To cater this problem, wide range materials have been added producing sturdy composite materials. For instance, incorporation adhesive peptide natural polymer or synthetic moieties creates improved material, which not only possesses better mechanical properties compared native alginate, but grants additional capability In addition, drug release kinetic cell viability can be further when encapsulating agent. review, preparation various forms (fibre, bead, hydrogel, 3D-printed matrices) application described first, followed by discussion latest trend utilization dressing, delivery, engineering applications.

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ژورنال

عنوان ژورنال: Asian Journal of Pharmaceutical Sciences

سال: 2021

ISSN: ['1818-0876', '2221-285X']

DOI: https://doi.org/10.1016/j.ajps.2020.10.001